The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2019
Filed:
Jan. 26, 2015
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Nanna Albaek, Birkerød, DK;
Henrik Frydenlund Hansen, Ringsted, DK;
Susanne Kammler, Holte, DK;
Morten Lindow, Copenhagen, DK;
Jacob Ravn, Skovlunde, DK;
Mark Turner, Hoersholm, DK;
Assignee:
Hoffmann-La Roche, Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); C12N 2310/113 (2013.01); C12N 2310/315 (2013.01); C12N 2310/341 (2013.01); C12N 2310/345 (2013.01); C12N 2310/351 (2013.01); C12N 2310/51 (2013.01);
Abstract
The invention relates to the field of oligonucleotide therapeutics, and in particular to poly oligo oligonucleotides conjugates where two or more antisense oligonucleotides are covalently linked by physiologically labile linkers, and to a biocleavable functional group such as a conjugate group.