The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Oct. 20, 2017
Applicant:

Los Angeles Biomedical Research Institute AT Harbor-ucla Medical Center, Torrance, CA (US);

Inventors:

Alan J. Waring, Irvine, CA (US);

Frans J. Walther, Redondo Beach, CA (US);

Larry M. Gordon, Torrance, CA (US);

Robert H. Notter, Pittsford, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/00 (2006.01); C07K 14/47 (2006.01); A61K 38/16 (2006.01); A61K 45/06 (2006.01); C07K 7/08 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/001 (2013.01); A61K 38/16 (2013.01); A61K 45/06 (2013.01); C07K 7/08 (2013.01); C07K 14/00 (2013.01); C07K 14/47 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention relates to synthetic lung surfactant compositions that include a novel surface active peptide and a phospholipid, including phospholipase-resistant phospho-glycerol derivatives, phospholipase-resistant phospho-choline derivatives, naturally occurring phospholipids, or a combination thereof. Uses of the surfactant compositions of the present invention to treat endogenous surfactant dysfunctional or deficient lung tissue and to deliver therapeutic agents are also disclosed.


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