The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Jan. 12, 2018
Applicants:

H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);

Chongqing Zein Pharmaceutical Co., Ltd, Chongqing, CN;

Inventors:

Rongshi Li, Omaha, NE (US);

Said Sebti, Tampa, FL (US);

Yan Liu, Omaha, NE (US);

Yong Qin, Chongqing, CN;

Hao Song, Chengdu, CN;

Chunwei Cheng, Zhumadian, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/36 (2006.01); A01N 43/647 (2006.01); A01N 47/02 (2006.01); A61K 45/06 (2006.01); A61K 31/553 (2006.01); A61K 31/662 (2006.01); A61K 31/407 (2006.01); C07D 403/14 (2006.01); C07D 403/04 (2006.01); C07D 498/14 (2006.01); A61N 5/10 (2006.01); A61K 31/4192 (2006.01); C07F 9/6561 (2006.01);
U.S. Cl.
CPC ...
C07D 498/14 (2013.01); A01N 43/36 (2013.01); A01N 43/647 (2013.01); A01N 47/02 (2013.01); A61K 31/407 (2013.01); A61K 31/4192 (2013.01); A61K 31/553 (2013.01); A61K 31/662 (2013.01); A61K 45/06 (2013.01); A61N 5/10 (2013.01); C07D 403/04 (2013.01); C07D 403/14 (2013.01); C07F 9/6561 (2013.01);
Abstract

Marinopyrrole derivatives and methods for their synthesis and use are described herein. Novel cyclic and symmetric marinopyrroles with triazole substituents having antibacterial activity against resistant bacterial strains, such as MRSA are introduced. Also provided are methods of using the compounds for treating or preventing cancer and/or microbial infections.


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