The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Feb. 13, 2019
Applicant:

Cadila Healthcare Limited, Ahmedabad, Gujarat, IN;

Inventors:

Sanjay Jagdish Desai, Ahmedabad-Gujarat, IN;

Jayprakash Ajitsingh Parihar, Ahmedabad-Gujarat, IN;

Alpesh Pravinchandra Shah, Ahmedabad-Gujarat, IN;

Assignee:

Cadila Healthcare Limited, Ahmedabad, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 409/12 (2006.01); C07D 487/10 (2006.01); C07D 409/14 (2006.01); C07D 333/54 (2006.01); C07D 247/02 (2006.01); C07D 401/12 (2006.01); A61K 9/14 (2006.01); A61K 31/496 (2006.01); B01D 9/02 (2006.01);
U.S. Cl.
CPC ...
C07D 409/14 (2013.01); A61K 9/14 (2013.01); A61K 31/496 (2013.01); C07D 247/02 (2013.01); C07D 333/54 (2013.01); C07D 401/12 (2013.01); C07D 409/12 (2013.01); C07D 487/10 (2013.01); B01D 9/02 (2013.01);
Abstract

The present invention relates to Brexpiprazole having a purity of about 99.5% or more by area percentage of HPLC, having total impurities not more than 0.5% relative to brexpiprazole as measured by area percentage of HPLC, and having less than 0.1% 1-(benzo[b]thiophen-4-yl)piperazine or a salt thereof relative to brexpiprazole by area percentage of HPLC. The present invention also provides a composition comprising brexpiprazole having 1-(benzo[b]thiophen-4-yl)-piperazine or a salt thereof in an amount less than about 0.1% relative to brexpiprazole by area percentage of HPLC and process for the preparation of brexpiprazole.


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