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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10358439 B1

PDFFull Text
Date of Patent:
Jul. 23, 2019

Filed:

Sep. 16, 2016

Dna binding agents with a minor groove binding tail

Applicants:

Board of Regents, the University of Texas System, Austin, TX (US);

Board of Regents, the University of Texas System, Austin, TX (US);

Inventors:

Waldemar Priebe, Houston, TX (US);

Liwei Guo, Birmingham, AL (US);

Arkadiusz Kazimierski, Old Bridge, NJ (US);

Izabela Fokt, Houston, TX (US);

Charles Conrad;

Timothy Madden, Spring, TX (US);

Assignee:

Board of Regents, The University of Texas System, Austin, TX (US);

Attorney:

Parker Highlander PLLC

Primary Examiner:

Laura L Stockton

Int. Cl.
CPC ...
C07C 13/66 (2006.01); C07D 309/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07H 15/24 (2006.01); C07H 15/244 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); A61P 35/00 (2018.01); C07C 13/66 (2013.01); C07D 309/14 (2013.01); C07D 405/12 (2013.01); C07H 15/24 (2013.01); C07H 15/244 (2013.01);
Abstract

Provided herein are compounds which intercalate into the DNA of a cell and are capable of crossing the blood brain barrier of a formula provided herein. Pharmaceutical compositions of the compounds and methods of treating cancer, for example brain, lung, or pancreatic cancer, are also provided herein.

Find Patent Forward Citations

Priebe, Waldemar. (2019). Dna binding agents with a minor groove binding tail (U.S. Patent No. 10358439). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10358439

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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