The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Mar. 03, 2017
Applicants:

Genentech, Inc., South San Francisco, CA (US);

Constellation Pharmaceuticals, Inc., Cambridge, MA (US);

Inventors:

Brian K. Albrecht, Cambridge, MA (US);

Alexandre Cote, Cambridge, MA (US);

Terry Crawford, South San Francisco, CA (US);

Martin Duplessis, Cambridge, MA (US);

Andrew Charles Good, Cambridge, MA (US);

Yves LeBlanc, Cambridge, MA (US);

Steven Magnuson, South San Francisco, CA (US);

Christopher G. Nasveschuk, Cambridge, MA (US);

Richard Pastor, South San Francisco, CA (US);

F. Anthony Romero, South San Francisco, CA (US);

Alexander M. Taylor, Cambridge, MA (US);

Assignees:

GENENTECH, INC., South San Francisco, CA (US);

CONSTELLATION PHARMACEUTICALS, INC., Cambridge, MA (US);

Attorney:
Int. Cl.
CPC ...
C07D 249/12 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); A61K 31/53 (2006.01); A61K 31/4196 (2006.01); A61P 35/00 (2006.01); C07D 253/075 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
C07D 403/12 (2013.01); A61K 31/53 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C07D 249/12 (2013.01); C07D 253/075 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01);
Abstract

The present invention relates to methods for treating PCAF mediated disorders using a compound of formula (I) or a pharmaceutically acceptable salt thereof: wherein R, R-R, X, and each Rhave any of the values defined in the specification. Also included are novel compounds of formula (I) and salts thereof, as well as pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof.


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