The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 23, 2019
Filed:
Jun. 20, 2018
Applicant:
Ogeda SA, Gosselies, BE;
Inventors:
Hamid R. Hoveyda, Brussels, BE;
Didier Schils, Loupoigne, BE;
Ludivine Zoute, Vedrin, BE;
Julien Parcq, Lille, FR;
Assignee:
Epics Therapeutics, Gosselies, BE;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 295/10 (2006.01); C07D 207/16 (2006.01); C07D 277/06 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 405/10 (2006.01); C07D 407/06 (2006.01); C07D 409/10 (2006.01); C07D 413/10 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 207/16 (2013.01); C07D 277/06 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 405/10 (2013.01); C07D 407/06 (2013.01); C07D 409/10 (2013.01); C07D 413/10 (2013.01); C07D 413/12 (2013.01);
Abstract
The present invention is directed to a process for the preparation of aryl-carbonyl-pyrrolidine carboxylic acid derivative compounds which are useful in treating metabolic diseases, said process consisting of coupling a pyrrolidine ester compound with an aryl carboxylic acid derivative, followed by alkaline or acidic treatment, hydrogenolysis or treatment with a fluoride of the obtained intermediate, to afford novel aryl-carbonyl-pyrrolidine carboxylic acid derivative compounds.