The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Jul. 18, 2011
Applicants:

Christopher Paul Guise, Auckland, NZ;

David Francis Ackerley, Wellington, NZ;

Amir Ashoorzadeh, Manukau, NZ;

Janine Naomi Copp, Nelson, NZ;

Jack Urquhart Flanagan, Auckland, NZ;

Alexandra Marie Mowday, Auckland, NZ;

Adam Vorn Patterson, Waiheke Island, NZ;

Gareth Adrian Prosser, Wellington, NZ;

Jeffrey Bruce Smaill, Auckland, NZ;

Sophie Phillipa Syddall, Melbourne, AU;

Elsie May Williams, Wellington, NZ;

Inventors:

Christopher Paul Guise, Auckland, NZ;

David Francis Ackerley, Wellington, NZ;

Amir Ashoorzadeh, Manukau, NZ;

Janine Naomi Copp, Nelson, NZ;

Jack Urquhart Flanagan, Auckland, NZ;

Alexandra Marie Mowday, Auckland, NZ;

Adam Vorn Patterson, Waiheke Island, NZ;

Gareth Adrian Prosser, Wellington, NZ;

Jeffrey Bruce Smaill, Auckland, NZ;

Sophie Phillipa Syddall, Melbourne, AU;

Elsie May Williams, Wellington, NZ;

Assignees:

AUCKLAND UNISERVICES LIMITED, Auckland, NZ;

VICTORIA LINK LIMITED, Wellington, NZ;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/04 (2006.01); A61K 38/44 (2006.01); C12Q 1/26 (2006.01); A61K 47/54 (2017.01); C12N 9/02 (2006.01); C12N 9/06 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0495 (2013.01); A61K 38/44 (2013.01); A61K 47/556 (2017.08); C12N 9/0028 (2013.01); C12N 9/0036 (2013.01); C12Q 1/26 (2013.01); Y02A 50/473 (2018.01);
Abstract

The invention relates generally to bacterial nitroreductase enzymes and methods of use thereof: more particularly, although not exclusively, the enzymes have use in non-invasive imaging techniques, monitoring of therapeutic cell populations and gene-directed enzyme prodrug therapy. The invention also relates to the use of bacterial nitroreductase enzymes in radioimaging and/or ablation of biological agents and to compositions of use in such methods.


Find Patent Forward Citations

Loading…