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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10357576 B1

PDFFull Text
Date of Patent:
Jul. 23, 2019

Filed:

May. 08, 2013

18f-labelled folate/antifolate analogues

Applicant:

Merck & Cie, Schaffhausen, CH;

Inventors:

Roger Schibli, Baden, CH;

Rudolf Moser, Schaffhausen, CH;

Cristina Magdalena Mueller, Nussbaumen, CH;

Simon Mensah Ametamey, Zurich, CH;

Thomas Betzel, Hofheim am Taunus, DE;

Viola Groehn, Dachsen, CH;

Assignee:

MERECK & CIE, Schaffhusen, CH;

Attorneys:

Millen White Zelano and Branigan, PC

Csaba Henter

Primary Examiner:

Michael G Hartley

Assistant Examiner:

Sean R Donohue

Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 51/04 (2006.01); C07B 59/00 (2006.01); C07D 475/04 (2006.01); G01N 33/60 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0459 (2013.01); C07B 59/002 (2013.01); C07D 475/04 (2013.01); G01N 33/60 (2013.01); G01N 2333/705 (2013.01);
Abstract

The present invention is directed towards newF-folate/antifolate analog radiopharmaceuticals, wherein the phenyl group within folate structures has been replaced by anF-heterocycle, their precursors, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.

Find Patent Forward Citations

Schibli, Roger. (2019). 18f-labelled folate/antifolate analogues (U.S. Patent No. 10357576). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10357576

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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