The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Jul. 10, 2013
Applicant:

Transgene SA, Illkirch Graffenstaden, FR;

Inventors:

Emmanuel Tupin, Stockholm, SE;

Romain Micol, Lyons, FR;

Charles Antoine Coupet, Lyons, FR;

Geneviève Inchaupse, Lyons, FR;

Marie Gouanvic, Lyons, FR;

Nathalie Silvestre, Ergersheim, FR;

Jean-Baptiste Marchand, Obernai, FR;

Cécile Beny, Cerisiers, FR;

Assignee:

TRANSGENE SA, Illkirch Graffenstaden, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/04 (2006.01); C07K 14/35 (2006.01); C07K 16/12 (2006.01);
U.S. Cl.
CPC ...
A61K 39/04 (2013.01); C07K 14/35 (2013.01); C07K 16/1289 (2013.01); A61K 2039/51 (2013.01); A61K 2039/53 (2013.01); C07K 2319/00 (2013.01); C07K 2319/40 (2013.01);
Abstract

The present invention relates generally to immunogenic combinations comprising at least five antigens of aspecies as well as fusion thereof and nucleic acid molecules encoding such combined antigens and fusion. The present invention also relates to nucleic acid molecules, vectors, host cells and compositions comprising or encoding said combinations of mycobacterial antigens and fusion polypeptides as well as to methods for recombinantly producing them. The present invention also relates to methods of using said combinations of mycobacterial antigens, fusion polypeptides, vectors, host cells, compositions particularly for inducing or stimulating an immune response against ainfection or any disease caused by or associated with ainfection. The present invention also concerns antibodies directed to such mycobacterial antigens and fusion polypeptides that can be used in the diagnosis of ainfection and method of detection as well as kits of reagent comprising said combinations of mycobacterial antigens, fusion polypeptides, vectors, host cells, compositions or antibodies.


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