The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Feb. 04, 2015
Applicants:

Chuanju Liu, Orange, CT (US);

Jinlong Jian, River Edge, NJ (US);

Inventors:

Chuanju Liu, Orange, CT (US);

Jinlong Jian, River Edge, NJ (US);

Assignee:

New York University, New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/18 (2006.01); A61K 38/47 (2006.01); A61K 49/00 (2006.01); A61K 45/06 (2006.01); G01N 33/68 (2006.01); C07K 14/47 (2006.01); A01K 67/027 (2006.01); C12Q 1/6883 (2018.01);
U.S. Cl.
CPC ...
A61K 38/18 (2013.01); A01K 67/0276 (2013.01); A61K 38/47 (2013.01); A61K 45/06 (2013.01); A61K 49/0008 (2013.01); C07K 14/47 (2013.01); C12Q 1/6883 (2013.01); C12Y 302/01045 (2013.01); C12Y 302/01052 (2013.01); G01N 33/6893 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0306 (2013.01); A01K 2267/0356 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/47 (2013.01); G01N 2800/044 (2013.01);
Abstract

The present invention provides composition and methods for diagnosis and treatment of lysosomal storage diseases and their diagnosis and treatment, including Gaucher's Disease and Tay-Sachs disease, and particularly which utilize progranulin (PGRN), or active PGRN peptides, including atsttrin. The invention also provides animal models of lysosomal storage diseases, including Gaucher's Disease and Tay-Sachs disease, based on or including PGRN mutations including PGRN null mutants and PGRN gene knock outs.


Find Patent Forward Citations

Liu, Chuanju. (2019). Progranulin (pgrn) and its derivatives for diagnosis and treatment of lysosomal storage diseases (U.S. Patent No. 10357542). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10357542

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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