The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 23, 2019

Filed:

Jun. 21, 2017
Applicant:

Mannkind Corporation, Valencia, CA (US);

Inventors:

Keith A. Oberg, Valencia, CA (US);

Joseph Sulner, Paramus, NJ (US);

Marshall L. Grant, Newtown, CT (US);

Assignee:

MannKind Corporation, Westlake Village, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/08 (2019.01); C07K 7/06 (2006.01); A61Q 19/00 (2006.01); A61Q 19/08 (2006.01); A61Q 19/02 (2006.01); A61K 38/38 (2006.01); A61K 45/06 (2006.01); A61K 38/26 (2006.01); A61K 38/12 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 38/13 (2006.01); A61K 38/25 (2006.01); A61K 38/27 (2006.01); A61K 38/28 (2006.01); A61K 38/29 (2006.01); A61K 9/50 (2006.01); A61K 38/22 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1676 (2013.01); A61K 9/0073 (2013.01); A61K 9/167 (2013.01); A61K 9/1611 (2013.01); A61K 9/1617 (2013.01); A61K 9/1623 (2013.01); A61K 9/5052 (2013.01); A61K 9/5089 (2013.01); A61K 38/13 (2013.01); A61K 38/22 (2013.01); A61K 38/25 (2013.01); A61K 38/26 (2013.01); A61K 38/27 (2013.01); A61K 38/28 (2013.01); A61K 38/29 (2013.01);
Abstract

Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Types of surface properties that are altered by the disclosed methods include electrostatic properties, hydrophobic properties, and hydrogen bonding properties.


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