The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Oct. 13, 2017
Applicant:
President and Fellows of Harvard College, Cambridge, MA (US);
Inventors:
Adam Ezra Cohen, Cambridge, MA (US);
Joel Kralj, Louisville, CO (US);
Adam D. Douglass, Salt Lake City, UT (US);
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
H01M 8/16 (2006.01); G01N 33/68 (2006.01); C07K 14/195 (2006.01); G01N 33/566 (2006.01); C12N 15/62 (2006.01); C12N 15/85 (2006.01); C07K 14/00 (2006.01); C07K 14/435 (2006.01); C12N 7/00 (2006.01); C12N 15/86 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6872 (2013.01); C07K 14/00 (2013.01); C07K 14/195 (2013.01); C07K 14/43595 (2013.01); C12N 7/00 (2013.01); C12N 15/62 (2013.01); C12N 15/625 (2013.01); C12N 15/85 (2013.01); C12N 15/86 (2013.01); G01N 21/6486 (2013.01); G01N 33/566 (2013.01); C07K 2319/60 (2013.01); C12N 2740/15043 (2013.01); C12N 2750/14143 (2013.01); C12N 2810/00 (2013.01); G01N 2333/726 (2013.01);
Abstract
The invention provides methods, cells and constructs for optical measurement of membrane potential. These methods can be used in cells that are not accessible to presently available methods using electrodes. The methods can be directed to, for example, high-throughput drug screening assays to determine agents that can affect membrane potential of a target cell.