The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10352917 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 16, 2019

Filed:

Jan. 19, 2017
Applicant:

Dalian University of Technology, Dalian, Liaoning, CN;

Inventors:

Yuhan Zhou, Liaoning, CN;

Jingping Qu, Liaoning, CN;

Xiaoliang Dong, Liaoning, CN;

Assignee:

DALIAN UNIVERSITY OF TECHNOLOGY, Dalian, Liaoning, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/00 (2006.01); G01N 33/18 (2006.01); C07F 15/02 (2006.01); C09K 11/06 (2006.01); C09B 49/00 (2006.01); G01N 21/64 (2006.01); C07F 17/02 (2006.01); C09B 1/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/182 (2013.01); C07F 15/02 (2013.01); C07F 17/02 (2013.01); C09B 1/00 (2013.01); C09B 49/00 (2013.01); C09K 11/06 (2013.01); G01N 21/643 (2013.01); C09K 2211/1007 (2013.01); C09K 2211/1011 (2013.01); C09K 2211/1014 (2013.01); C09K 2211/187 (2013.01); G01N 2021/6439 (2013.01);
Abstract

The present invention provides a carboxylate-bridged binuclear iron-sulfur clusters fluorescent probe having the structure of Formula I. The preparation method comprises the following steps: anthracenylmethanamine and p-methoxycarbonylphenyl isocyanate have an addition reaction to get a substitutional methyl benzoate, which is hydrolyzed to get a corresponding carboxylic acid; react the resulting carboxylic acid with alkali to get carboxylate, and then coordinate with binuclear iron precursor to obtain the fluorescent probe. Compared with the prior art, the invention firstly provides the carboxylate-bridged binuclear iron-sulfur clusters of metal complex which similar to the central structure of bio-enzyme. The metal complex, as a fluorescent probe, has good selectivity to the fluorinion detection. The fluorescence titration experiment is simple and easy to operate and the fluorescence changes are sensitive.


Find Patent Forward Citations

Zhou, Yuhan. (2019). Carboxylate-bridged binuclear iron-sulfur clusters fluorescent probe, preparation method and application thereof (U.S. Patent No. 10352917). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10352917

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