The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Aug. 27, 2015
Applicant:
The United States of America, As Represented BY the Secretary Department of Health and Human Services, Washington, DC (US);
Inventors:
Zhijian Wu, Gaithersburg, MD (US);
Anand Swaroop, Bethesda, MD (US);
Suddhasil Mookherjee, Rockville, MD (US);
Suja Hiriyanna, Boyds, MD (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/63 (2006.01); C12N 15/10 (2006.01); C07K 14/47 (2006.01); A61K 31/7088 (2006.01); C12N 9/22 (2006.01); C12N 15/113 (2010.01); C12N 15/86 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1024 (2013.01); A61K 31/7088 (2013.01); C07K 14/4702 (2013.01); C12N 9/22 (2013.01); C12N 15/113 (2013.01); C12N 15/86 (2013.01); A61K 48/00 (2013.01); A61K 48/005 (2013.01); C12N 2310/10 (2013.01); C12N 2750/14145 (2013.01);
Abstract
Expression vectors, viral particles and therapeutic methods of using such constructs to improve the visual function of a patient suffering from diseases of the eye, resulting from failure to produce a specific protein in the eye, or the production of a non-functional protein in the eye, particularly Leber Congenital Amaurosis (LCA) and CEP290-related LCA.