The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Mar. 17, 2016
Applicant:
Genmab A/s, Copenhagen, DK;
Inventors:
Janine Schuurman, Diemen, NL;
Tom Vink, Alphen aan den Rijn, NL;
Jan Van De Winkel, Zeist, NL;
Aran Frank Labrijn, Nigtevecht, NL;
Paul Parren, Odijk, NL;
Willem Karel Bleeker, Amsterdam, NL;
Frank Beurskens, Culemborg, NL;
Patrick Van Berkel, Utrecht, NL;
Assignee:
GENMAB A/S, Copenhagen V, DK;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); A61K 39/00 (2006.01); C12N 15/85 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2887 (2013.01); C07K 16/00 (2013.01); C07K 16/283 (2013.01); C07K 16/2863 (2013.01); C12N 15/8509 (2013.01); A01K 2227/105 (2013.01); A01K 2267/01 (2013.01); C07K 2317/21 (2013.01); C07K 2317/55 (2013.01); C07K 2317/732 (2013.01); C07K 2317/77 (2013.01); C07K 2317/90 (2013.01); C12N 2740/16011 (2013.01);
Abstract
The invention relates to novel non-human transgenic animals, which upon antigenic stimulation are capable of producing monovalent antibodies binding to a selected antigen, modified heavy chain transgenes, methods for producing the non-human transgenic animals, methods for immunizing the non-human transgenic animals for as well as monovalent antibodies obtainable by such immunization methods.