The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Aug. 06, 2015
Applicant:
Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;
Inventors:
Tomoaki Komai, Tokyo, JP;
Takako Kimura, Tokyo, JP;
Daichi Baba, Tokyo, JP;
Yoshikuni Onodera, Tokyo, JP;
Kento Tanaka, Kanagawa, JP;
Takashi Kagari, Kanagawa, JP;
Anri Aki, Saitama, JP;
Nobumi Nagaoka, Saitama, JP;
Assignee:
Daiichi Sankyo Company, Limited, Tokyo, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); C12N 5/10 (2006.01); C12N 15/09 (2006.01); C07K 16/46 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 39/395 (2013.01); C07K 16/18 (2013.01); C07K 16/46 (2013.01); C12N 5/10 (2013.01); C12N 15/09 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/71 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01);
Abstract
It is intended to provide a therapeutic and/or prophylactic agent for transplant rejections, immunological diseases, allergic diseases, inflammatory diseases, thrombosis, cancers, etc., targeting human Orai1. The present invention provides, for example, a pharmaceutical composition comprising an antibody that specifically recognizes human Orai1 and has the activity of inhibiting human T cell activation.