The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10351609 B1

PDF
Full Text
Expired
Date of Patent:
Jul. 16, 2019

Filed:

Feb. 10, 2017
Applicant:

Medical Diagnostic Laboratories, Llc, Hamilton, NJ (US);

Inventors:

Elisa A Waxman, Philadelphia, PA (US);

Thais Acquafreda, Philadelphia, PA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C12N 9/02 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4703 (2013.01); C07K 14/4705 (2013.01); C12N 9/0069 (2013.01); C12Y 113/12007 (2013.01); C12Y 207/11001 (2013.01); G01N 33/5011 (2013.01); G01N 2333/91215 (2013.01); G01N 2800/52 (2013.01);
Abstract

Disclosed are methods of determining activity of mTOR variants upon exposure to mTOR inhibitors, such a rapamycin or rapalogs thereof, methods for determining kinase activity of a mTOR variant, and methods for determining tumor cell response to treatment with rapamycin or rapalogs thereof. A method for determining whether a compound inhibits mTOR activity in a cell is also disclosed.


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Waxman, Elisa. (2019). Cell-based assay for determining mtor activity (U.S. Patent No. 10351609). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10351609

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