The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Mar. 21, 2016
Applicant:
The Regents of the University of California, Oakland, CA (US);
Inventors:
Timothy J. Deming, Los Angeles, CA (US);
Eric G. Gharakhanian, Los Angeles, CA (US);
Assignee:
The Regents of the University of California, Oakland, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/00 (2006.01); C07K 7/06 (2006.01); C08G 69/10 (2006.01); C08G 69/48 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 1/006 (2013.01); C07K 7/06 (2013.01); C08G 69/10 (2013.01); C08G 69/48 (2013.01); G01N 33/68 (2013.01);
Abstract
Some embodiments of the invention involve methods for introduction of various functional groups onto polypeptides, peptides and proteins by alkylation of thioether (a.k.a. sulfide) groups by ring opening reactions, creating new compositions of matter that may be useful for medical therapeutic or diagnostic applications. The thioether groups may either be present in the polypeptides, or may be added to polypeptides by chemical modification, such as by alkylation of thiol (sulfhydryl) groups.