The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Aug. 18, 2017
Applicant:
Oncternal Therapeutics, Inc., San Diego, CA (US);
Inventor:
Stephen E. Webber, San Diego, CA (US);
Assignee:
Oncternal Therapeutics, Inc., San Diego, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 413/06 (2006.01); C07D 409/06 (2006.01); C07D 403/06 (2006.01); C07D 209/34 (2006.01); C07D 401/06 (2006.01); C07D 209/40 (2006.01); C07D 209/38 (2006.01); C07D 417/06 (2006.01); C07D 405/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 209/34 (2013.01); C07D 209/38 (2013.01); C07D 209/40 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 405/06 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01); C07D 417/06 (2013.01);
Abstract
Indoline derivative compounds that act as EWS-FLI1 transcription factor inhibitors are provided. Also provided are pharmaceutical compositions of the indoline derivatives, methods of synthesizing the same, methods of treating using same, and assays for identifying the inhibitors of EWS-FLI1 oncoprotein.