The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 16, 2019

Filed:

Oct. 06, 2016
Applicants:

Glaxosmithkline Intellectual Property Development Limited, Brentford, Middlesex, GB;

Astex Therapeutics Limited, Cambridge, Cambridgeshire, GB;

Inventors:

James Callahan, King of Prussia, PA (US);

Jeffrey K. Kerns, King of Prussia, PA (US);

Tindy Li, King of Prussia, PA (US);

Brent W. McCleland, King of Prussia, PA (US);

Hong Nie, King of Prussia, PA (US);

Joseph E. Pero, Anderson, SC (US);

Thomas Glanmor Davies, Cambridge, GB;

Charlotte Mary Griffiths-Jones, Cambridge, GB;

Thomas Daniel Heightman, Cambridge, GB;

Steven Howard, Cambridge, GB;

David Norton, Cambridge, GB;

Marinus Leendert Verdonk, Cambridge, GB;

Alison Jo-Anne Woolford, Cambridge, GB;

Assignees:

GlaxoSmithKline Intellectual Property Development Limited, Brentford, Middlesex, GB;

Astex Therapeutics Limited, Cambridge, Cambridgeshire, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/14 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/10 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/08 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
C07D 231/14 (2013.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/08 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01);
Abstract

The present invention relates to arylcyclohexyl pyrazole compounds of Formula (I) methods of making them, pharmaceutical compositions containing them and their use as NRF2 regulators.


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