The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Jul. 23, 2018
Applicant:
Hovione Scientia Limited, Loughbeg, Ringaskiddy, Cork, IE;
Inventors:
Zita Mendes, Lisbon, PT;
Constanca Cacela, Lisbon, IT;
Gloria Ten Figas, Amsterdam, NL;
Ana Fernandez Casares, Amsterdam, NL;
Assignee:
Hovione Scientia Limited, Ringaskiddy, Cork, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 237/26 (2006.01); A61K 31/65 (2006.01);
U.S. Cl.
CPC ...
C07C 237/26 (2013.01); A61K 31/65 (2013.01); C07B 2200/13 (2013.01);
Abstract
Described are new forms of crystalline minocycline base. In particular, two new crystalline polymorphic forms, designated Form IV and Form V of minocycline base are provided. These are characterized by XRD, FTIR and TGA. Processes for preparing the new polymorphic forms and their use in pharmaceutical compositions are also provided. Form IV and Form V are prepared by dissolving and/or suspending minocycline base in an organic solvent followed by crystallization.