The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Oct. 23, 2017
Applicant:
Medgenome Inc., Foster City, CA (US);
Inventors:
Amitabha Chaudhuri, Redwood City, CA (US);
Ravi Gupta, Bangalore, IN;
Priyanka Shah, Uttar Pradesh, IN;
Malini Manoharan, Bangalore, IN;
Kiran V. Paul, Kerala, IN;
Rohit Gupta, Bangalore, IN;
Assignee:
MedGenome Inc., Foster City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 4/00 (2006.01); A61K 39/00 (2006.01); C12Q 1/6886 (2018.01); G16B 20/00 (2019.01); G16B 35/00 (2019.01); G16C 20/60 (2019.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); C12Q 1/6886 (2013.01); G16B 20/00 (2019.02); G16B 35/00 (2019.02); G16C 20/60 (2019.02); A61K 2039/5154 (2013.01); A61K 2039/5158 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01);
Abstract
The invention describes a method for identifying T-cell activating neo-epitopes from all genetically altered proteins. The mutated proteins contribute to neo-epitopes after they are proteolytically degraded within antigen presenting cells, such as dendritic cells and macrophages.