The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Apr. 24, 2015
Applicant:
Chugai Seiyaku Kabushiki Kaisha, Kita-ku, Tokyo, JP;
Inventors:
Takashi Tomimatsu, Tokyo, JP;
Kensuke Okazaki, Tokyo, JP;
Yumi Ogawa, Tokyo, JP;
Takahiro Yamamura, Tokyo, JP;
Assignee:
CHUGAI SEIYAKU KABUSHIKI KAISHA, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 47/20 (2006.01); A61K 47/36 (2006.01); A61K 47/38 (2006.01); A61K 9/16 (2006.01); A61K 9/48 (2006.01); C07D 401/04 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 9/16 (2013.01); A61K 9/1617 (2013.01); A61K 9/1652 (2013.01); A61K 9/48 (2013.01); A61K 47/20 (2013.01); A61K 47/36 (2013.01); A61K 47/38 (2013.01); C07D 401/04 (2013.01);
Abstract
An improved solubility of a pharmaceutical composition or formulation containing a large amount of 9-ethyl-6,6-dimethyl-8-(4-morpholin-4-yl-piperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile or a salt thereof can be achieved by forming granules of the compound or salt thereof and allowing the granules to be present together with a disintegrating agent.