The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 16, 2019
Filed:
Jun. 13, 2018
Applicant:
Genfit, Loos, FR;
Inventors:
Raphael Darteil, Lille, FR;
Rémy Hanf, Lille, FR;
Dean Hum, Bondues, FR;
Ingrid Dufour, Wattignies, FR;
Assignee:
GENFIT, Loos, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/192 (2006.01); A61K 31/426 (2006.01); A61K 31/381 (2006.01); A61K 31/222 (2006.01); A61K 31/216 (2006.01); A61K 31/155 (2006.01); A61K 38/28 (2006.01); A61K 45/06 (2006.01); A61K 9/20 (2006.01); C07C 321/26 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 9/20 (2013.01); A61K 31/155 (2013.01); A61K 31/216 (2013.01); A61K 31/222 (2013.01); A61K 31/381 (2013.01); A61K 31/426 (2013.01); A61K 38/28 (2013.01); A61K 45/06 (2013.01); C07C 321/26 (2013.01);
Abstract
The invention provides 1,3-diphenylprop-2-en-1-one derivatives and pharmaceutical compositions comprising the same for treating liver disorders, in particular those requiring the reduction of plasma level of biochemical markers such as aminotransferases. The 1,3-diphenylprop-2-en-1-one derivatives of General Formula (I) have hepatoprotective properties and can be used in methods for treating liver disorders involving the pathological disruption, inflammation, degeneration, and/or proliferation of liver cells, such as liver fibrosis or fatty liver disease.