The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2019
Filed:
Sep. 23, 2016
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Johann Karl, Peissenberg, DE;
Ursula-Henrike Wienhues-Thelen, Krailling, DE;
Dirk Block, Bichl, DE;
Christian Zaugg, Rheinfelden, CH;
Hans-Peter Brunner, Muenchenstein, CH;
James Januzzi, Wellesley, MA (US);
Andre Ziegler, Laeufelfingen, CH;
Julian Braz, Greenwood, IN (US);
Thomas Dieterle, Freiburg, DE;
Edelgard Kaiser, Huenenberg See, CH;
Roche Diagnostics Operations, Inc., Indianapolis, IN (US);
Abstract
Disclosed herein is a method for diagnosing and/or grading diastolic dysfunction or at least one structural or functional abnormality associated with diastolic dysfunction. The method involves measuring the level of IGFBP7 (Insulin like growth factor binding protein 7) and, optionally, the level of at least one further marker in a patient suffering from heart failure, and comparing the level to a reference level. Also disclosed is a method of monitoring diastolic function in a patient suffering from heart failure, and kits and devices for performing the method.