The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2019
Filed:
Aug. 17, 2017
Sapient Sensors Limited, County Durham, GB;
Stephen Lee Cash, Yorkshire, GB;
Keith Robson, Durham, GB;
Ian Anthony Kinloch, Lancashire, GB;
Peter George Stockley, Yorkshire, GB;
Sapient Sensors Limited, Durham, GB;
Abstract
A device for identifying the presence of a specific target molecule or biomarker by the detection of a change in an electrical property includes a measurement sensorcomprising a semiconducting sensor structurecapable of conjugating with the biomarker, thus giving rise to the said change in electrical property, and an electrode systemfor conducting a signal from the device. According to the invention there is a further such sensor, of substantially identical form but having its sensor structurealready conjugated with the biomarker, or otherwise capped, e.g. using a further oligonucleotide strand, so as to act as an internal reference. When a biological sample, e.g. saliva, is applied to the electrodes, the reference enables the discounting of all environmental effects other than the biomarker. The invention provides a simple, cheap and accurate test for one or more biomarkers that can be used in the field without complex equipment.