The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2019
Filed:
Mar. 12, 2014
Applicant:
Mylan Inc., Canonsburg, PA (US);
Inventors:
Jeffrey P. Smith, Morgantown, WV (US);
Peter E. Lipsky, Charlottesville, VA (US);
Assignee:
MYLAN INC., Canonsburg, PA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6883 (2018.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The invention describes assays for determining the potency of a test lot of glatiramer acetate (GA) by quantitating and comparing the levels of mRNA response biomarkers produced in mouse T-cells in response to stimulation with the test lot or a reference standard lot of GA, wherein the T-cells are obtained from mice immunized with the test lot or the reference standard lot of GA. Methods for identifying mRNA response biomarkers useful in the assays of the invention also are described.