The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2019

Filed:

Aug. 11, 2015
Applicant:

Agency for Science, Technology and Research, Singapore, SG;

Inventors:

Farid Ghadessy, Biopolis, SG;

Jia Wei Siau, Singapore, SG;

Peter Droge, Singapore, SG;

Harshyaa Makhija, Singapore, SG;

Shree Harsh Vijaya Chandra, Singapore, SG;

Sabrina Peter, Singapore, SG;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01); C12N 9/22 (2006.01); C12N 1/15 (2006.01); C12N 1/21 (2006.01); C12P 19/34 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/907 (2013.01); C12N 9/1241 (2013.01); C12N 9/22 (2013.01); C12N 15/90 (2013.01); C12N 2795/10322 (2013.01);
Abstract

The present invention refers to lambda integrases comprising at least one amino acid mutation at positions 43, 319 and 336 of the lambda integrase as set forth in SEQ ID NO: 1. The invention further refers to nucleic acid molecules comprising the nucleotide sequence encoding the mutant lambda integrase and to host cells containing these nucleic acid molecules. The invention also refers to methods of recombining a nucleic acid of interest into a target nucleic acid in the presence of the mutant lambda integrase and sequence specific recombination kits.


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