The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2019

Filed:

Feb. 03, 2016
Applicants:

Neurimmune Holding Ag, Schlieren, CH;

University of Zurich, Zurich, CH;

Inventors:

Fabio Montrasio, Schindellegi, CH;

Maria Grazia Barenco Montrasio, Schindellegi, CH;

Jan Grimm, Dubendorf, CH;

Roger Nitsch, Zumikon, CH;

Christoph Hock, Erlenbach, CH;

Tobias Welt, Zurich, CH;

Jordan Mcafoose, Zurich, CH;

Marcel Maier, Zurich, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/40 (2006.01); A61K 39/00 (2006.01); C07K 14/435 (2006.01); C12N 9/02 (2006.01); A61K 45/06 (2006.01); A61K 49/08 (2006.01); A61K 51/10 (2006.01); G01N 33/573 (2006.01); G01N 33/577 (2006.01); A61K 47/68 (2017.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 39/0005 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); A61K 47/6871 (2017.08); A61K 49/085 (2013.01); A61K 51/10 (2013.01); C07K 14/435 (2013.01); C12N 9/0089 (2013.01); G01N 33/573 (2013.01); G01N 33/577 (2013.01); G01N 33/6893 (2013.01); A61K 2039/505 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/30 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/92 (2013.01); G01N 2333/90283 (2013.01); G01N 2800/28 (2013.01); G01N 2800/285 (2013.01);
Abstract

Provided are novel human copper-zinc superoxide dismutase, also known as superoxide dismutase 1 or SOD1, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for SOD1 are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for SOD1 targeted immunotherapy and diagnosis, respectively.


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