The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2019

Filed:

Apr. 17, 2015
Applicant:

Shinshu University, Nagano, JP;

Inventors:

Shun-ichiro Taniguchi, Nagano, JP;

Yasuto Akiyama, Shizuoka, JP;

Takeshi Masaki, Nagano, JP;

Hitomi Shimizu, Nagano, JP;

Assignee:

Shinshu University, Nagano, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/32 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 35/74 (2015.01); C12N 15/00 (2006.01); C12N 15/09 (2006.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2863 (2013.01); A61K 35/74 (2013.01); A61K 39/395 (2013.01); C07K 16/32 (2013.01); C12N 15/00 (2013.01); C12N 15/09 (2013.01); C12P 21/005 (2013.01); C07K 2317/24 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); C07K 2319/02 (2013.01);
Abstract

It is an object of the present invention to provide signal sequence information capable of secreting an antibody to the outside of cells in generation of the antibody by microorganisms of genus, and an antibody expression vector capable of secreting an antibody to the outside of cells by utilizing the signal sequence information. As a means for achieving the aforementioned object, there is prepared, which is transformed with a vector having inserted thereinto a DNA insert comprising the 5'-terminus of an antibody gene linked to the 3′-terminus of a DNA encoding a signal peptide-linker conjugate having a linker linked to the C-terminus of a signal peptide consisting of an amino acid sequence shown in SEQ ID NO: 1.


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