The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2019
Filed:
May. 09, 2017
Applicant:
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Stefan Dengl, Munich, DE;
Peter Michael Huelsmann, Habach, DE;
Christian Gassner, Penzberg, DE;
Sebastian Breuer, Penzberg, DE;
Olaf Mundigl, Weilheim, DE;
Guy Georges, Habach, DE;
Ralf Schumacher, Penzberg, DE;
Guido Hartmann, Loerrach, DE;
Sabine Gruener, Grenzach-Wyhlen, DE;
Assignee:
Hoffman-La Roche, Inc., Little Falls, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/24 (2006.01); C07K 16/22 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/245 (2013.01); C07K 16/22 (2013.01); A61K 2039/507 (2013.01); C07K 2299/00 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract
Herein are reported humanized anti-IL-1beta antibodies that are humanized variants of the murine anti-IL-1beta antibody H34. A specific humanized antibody comprises (a) a HVR-H1 comprising the amino acid sequence of SEQ ID NO: 25, (b) a HVR-H2 comprising the amino acid sequence of SEQ ID NO: 27, and (c) a HVR-H3 comprising the amino acid sequence of SEQ ID NO: 28.