The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 09, 2019

Filed:

Dec. 29, 2016
Applicant:

Shanghai Pharmaceuticals Holding Co., Ltd., Shanghai, CN;

Inventors:

Jianxin Yu, Shanghai, CN;

Yu Hao, Shanghai, CN;

Jing Zhang, Shanghai, CN;

Fei Zhao, Shanghai, CN;

Leduo Zhang, Shanghai, CN;

Zhenying Liu, Shanghai, CN;

Gongsheng Li, Shanghai, CN;

Yuji Wang, Shanghai, CN;

Na Chen, Shanghai, CN;

Rui Bai, Shanghai, CN;

Yi Fan, Shanghai, CN;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/4985 (2006.01); C07C 59/255 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4985 (2013.01); C07C 59/255 (2013.01); C07B 2200/13 (2013.01);
Abstract

Disclosed is a salt of a quinoline derivative, polymorphic forms thereof, preparation methods thereof, a composition, and applications. The SPH1772 ditartrate or crystal form A thereof expresses the following excellent properties: high stability, great bioavailability, excellent pharmacokinetic properties, and better in vivo efficacy than SPH1772 free base.


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