The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2019
Filed:
Sep. 30, 2016
Virginia Commonwealth University, Richmond, VA (US);
Martin K. Safo, Richmond, VA (US);
Yan Zhang, Glen Allen, VA (US);
Mohini Ghatge, Glen Allen, VA (US);
Osheiza Abdulmalik, Philadelphia, PA (US);
Abdelsattar Mansour Ebid Omar, Jeddah, SA;
Moustafa El-Sayed El-Araby, Jeddah, SA;
VIRGINIA COMMONWEALTH UNIVERSITY, Richmond, VA (US);
KING ABDULAZIZ UNIVERSITY, Jeddah, SA;
THE CHILDREN'S HOSPITAL OF PHILADELPHIA, Philadelphia, PA (US);
Abstract
Azolylacryloyl derivatives with hypoxic properties are provided. The compounds have a generic formula: and are suitable for treating sickle cell disease and hypoxia-underlying diseases, e.g. hemorrhagic and traumatic shock, cardiac arrest and cardiogenic shock, traumatic brain injury, cancer, stroke, myocardial infarction, myocardial ischemia, vaso-occlusive crisis, etc.