The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2019
Filed:
Aug. 21, 2015
The Charles Stark Draper Laboratory, Inc., Cambridge, MA (US);
Johnson & Johnson Innovation Llc, Somerville, NJ (US);
Joseph L. Charest, Cambridge, MA (US);
Martin Nohilly, Murray Hill, NJ (US);
Christopher Dibiasio, Stoughton, MA (US);
Jeffrey T. Borenstein, Newton, MA (US);
Mark Laurenzi, Mountain Lakes, NJ (US);
Jonathan Wilson, Mattapoisett Center, MA (US);
THE CHARLES STARK DRAPER LABORATORY INC., Cambridge, MA (US);
Abstract
A microfluidic device for increasing convective clearance of particles from a fluid is provided. In some implementations, described herein the microfluidic device includes multiple layers that each define infusate, blood, and filtrate channels. Each of the channels have a pressure profile. The device can also include one or more pressure control features. The pressure control feature controls a difference between the pressure profiles along a length of the device. For example, the pressure control feature can control the difference between the pressure profile of the filtrate channel and the pressure profile of the blood channel. In some implementations, the pressure control feature controls the pressure difference between two channels such that the difference varies along the length of the channels by less than 50% of the pressure difference between the channels at the channels' inlets.