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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10342865 B1

PDFFull Text
Date of Patent:
Jul. 09, 2019

Filed:

May. 12, 2017

Method for treating epstein-barr virus—positive cancer with immunotherapy

Applicants:

Agency for Science, Technology and Research, Singapore, SG;

Tessa Therapeutics Pte. Ltd., Singapore, SG;

Singapore Health Services Pte. Ltd., Singapore, SG;

Inventors:

John Connolly, Singapore, SG;

Richard Hopkins, Singapore, SG;

Han Chong Toh, Singapore, SG;

Assignees:

TESSA THERAPEUTICS PTE. LTD, Singapore, SG;

SINGAPORE HEALTH SERVICES PTE. LTD., Singapore, SG;

AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH, Singapore, SG;

Attorney:

Adsero IP

Primary Examiner:

Nicole Kinsey White

Int. Cl.
CPC ...
A61K 35/17 (2015.01); C12Q 1/68 (2018.01); C12Q 1/6886 (2018.01); G01N 33/574 (2006.01); A61K 39/245 (2006.01); C12N 7/00 (2006.01); C12Q 1/70 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/245 (2013.01); A61K 35/17 (2013.01); C12N 7/00 (2013.01); C12Q 1/68 (2013.01); C12Q 1/6886 (2013.01); C12Q 1/701 (2013.01); C12Q 1/705 (2013.01); G01N 33/574 (2013.01); G01N 33/57407 (2013.01); G01N 33/57423 (2013.01); G01N 33/57438 (2013.01); G01N 33/57446 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/545 (2013.01); A61K 2039/57 (2013.01); A61K 2039/572 (2013.01); A61K 2039/585 (2013.01); C12N 2710/16234 (2013.01); C12N 2710/16271 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/05 (2013.01); G01N 2333/521 (2013.01); G01N 2333/57 (2013.01); G01N 2800/52 (2013.01);
Abstract

A method for predicting whether a patient will be a long-term survivor on treatment of a disease by adoptive cell transfer (ACT), is disclosed comprising: (i) analyzing a blood-derived sample obtained from the patient for one or more prognostic markers of long-term survival on treatment of a disease by ACT, and; (ii) based on the analysis of step (i), predicting whether the patient will be a long-term survivor on treatment of the disease by ACT. Also disclosed are methods for treating a patient by ACT, methods for selecting a patient for treatment by ACT, and methods for selecting a patient for treatment of a disease by ACT.

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