The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2019
Filed:
Apr. 04, 2018
Gilead Sciences, Inc., Foster City, CA (US);
Peter A. Blomgren, Issaquah, WA (US);
Kevin S. Currie, North Bend, WA (US);
Jeffrey E. Kropf, Issaquah, WA (US);
Seung H. Lee, Branford, CT (US);
Jennifer R. Lo, Branford, CT (US);
Scott A. Mitchell, East Haven, CT (US);
Aaron C. Schmitt, Hamden, CT (US);
Sundaramoorthi Swaminathan, Burlingame, CA (US);
Jin-Ming Xiong, Guilford, CT (US);
Jianjun Xu, Seattle, WA (US);
Zhongdong Zhao, Guilford, CT (US);
Gilead Sciences, Inc., Foster City, CA (US);
Abstract
The present disclosure relates to compounds that are Syk inhibitors and to their use in the treatment of various disease states, including cancer and inflammatory conditions. In particular embodiments, the structure of the compounds is given by Formula I: wherein R, R, R, and Rare as described herein. The present disclosure further provides pharmaceutical compositions that include a compound of Formula I, or pharmaceutically acceptable salts or co-crystals thereof, and methods of using these compounds and compositions to treat conditions mediated by Syk.