The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 09, 2019
Filed:
Nov. 04, 2016
Applicant:
Askat Inc., Aichi, JP;
Inventors:
Naoko Ohtani, Tokyo, JP;
Fumitaka Kamachi, Tokyo, JP;
Tze Mun Loo, Tokyo, JP;
Shinichi Koizumi, Aichi, JP;
Takako Okumura, Aichi, JP;
Assignee:
AskAt Inc., Aichi, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4412 (2006.01); A61P 35/00 (2006.01); A61K 31/192 (2006.01); A61K 31/44 (2006.01); A61K 45/06 (2006.01); A61K 31/64 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4412 (2013.01); A61K 31/192 (2013.01); A61K 31/44 (2013.01); A61K 31/64 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01);
Abstract
This invention is directed to prostaglandin E2 receptor 4 (EP4) antagonists useful in the treatment of nonalcoholic steatohepatitis (NASH)-associated liver cancer in a human or animal. The method comprises administering one or more of Compound A, Compound B or Compound C, or pharmaceutically acceptable salts thereof, as the EP4 antagonist(s). The method may include a pharmaceutical composition comprising the EP4 antagonist, and may include one or more other active agents and/or therapies.