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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10342758 B1

PDFFull Text
Date of Patent:
Jul. 09, 2019

Filed:

Jul. 08, 2013

Cationic lipid

Applicant:

Kyowa Hakko Kirin Co., Ltd., Tokyo, JP;

Inventors:

Takeshi Kuboyama, Tokyo, JP;

Tomohiro Era, Tokyo, JP;

Tomoyuki Naoi, Tokyo, JP;

Kaori Yagi, Tokyo, JP;

Shintaro Hosoe, Tokyo, JP;

Assignee:

KYOWA HAKKO KIRIN CO., LTD., Tokyo, JP;

Attorney:

Wenderoth, Lind & Ponack, L.L.P

Primary Examiner:

Celeste A Roney

Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 9/51 (2006.01); A61K 47/16 (2006.01); A61K 47/54 (2017.01); C12N 15/11 (2006.01); C12N 15/88 (2006.01); A61K 31/713 (2006.01); C07C 211/21 (2006.01); C07C 215/08 (2006.01); C07C 215/10 (2006.01); C07C 217/08 (2006.01); C07C 229/12 (2006.01); C07C 237/06 (2006.01); C07C 271/12 (2006.01); C07C 271/16 (2006.01); C07D 207/06 (2006.01); C07D 207/08 (2006.01); C07D 207/09 (2006.01); C07D 211/06 (2006.01); C07D 211/22 (2006.01); A61K 31/7088 (2006.01);
U.S. Cl.
CPC ...
A61K 9/00 (2013.01); A61K 9/51 (2013.01); A61K 31/713 (2013.01); A61K 47/16 (2013.01); A61K 47/54 (2017.08); C07C 211/21 (2013.01); C07C 215/08 (2013.01); C07C 215/10 (2013.01); C07C 217/08 (2013.01); C07C 229/12 (2013.01); C07C 237/06 (2013.01); C07C 271/12 (2013.01); C07C 271/16 (2013.01); C07D 207/06 (2013.01); C07D 207/08 (2013.01); C07D 207/09 (2013.01); C07D 211/06 (2013.01); C07D 211/22 (2013.01); C12N 15/11 (2013.01); C12N 15/88 (2013.01); A61K 31/7088 (2013.01);
Abstract

Provided are a cationic lipid which facilitates the introduction of a nucleic acid into, for example, a cell or the like; a composition containing the cationic lipid and a nucleic acid; a method for introducing a nucleic acid into a cell by using a composition containing the cationic lipid and the nucleic acid; and the like. The cationic lipid is, for example, a cationic lipid represented by formula (A): formula (A): (wherein Ris alkenyl or the like, Ris alkenyl or the like, Rand Rare each alkyl, or are combined together to form alkylene, or Rand Rare combined together to form alkylene, Ris a hydrogen atom or the like, or is combined together with Rto form alkylene, Xis alkylene, and Xis a single bond or alkylene).

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