The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

Aug. 17, 2016
Applicant:

Uvic Industry Partnerships Inc., Victoria, CA;

Inventors:

Fraser Hof, Victoria, CA;

Graham A. E. Garnett, Vancouver, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/00 (2006.01); G01N 30/06 (2006.01); C08B 37/00 (2006.01); C08B 15/00 (2006.01); C08F 257/02 (2006.01); B01J 20/281 (2006.01); C08B 37/02 (2006.01);
U.S. Cl.
CPC ...
G01N 30/482 (2013.01); C08B 15/00 (2013.01); C08B 37/0021 (2013.01); C08F 257/02 (2013.01); G01N 30/06 (2013.01); G01N 2030/067 (2013.01);
Abstract

Disclosed herein are embodiments of compounds, conjugates, and devices, such as columns comprising such compounds and/or conjugates, that can be used to identify, separate, and quantify post-translationally modified analytes. The disclosed compounds and conjugates can be used to discriminate between analytes, such as peptides, having different post-translation modifications, such as methylations, phosphorylations, acetylations, citrullinations, hydroxylations, nitrosylations, ADP-ribosylations, glycosylations, propionylations, butyrylations, crotonylations, 2-hydroxyisobutyrylations, malonylations, succinylations, formylations, ubiquitinations, neddylations, proline cis-trans isomerizations. In particular disclosed embodiments, the compounds and conjugates can be used to separate peptides having different degrees of methylation.


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