The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

Oct. 14, 2016
Applicant:

Korea Advanced Institute of Science and Technology, Daejeon, KR;

Inventors:

Byong-Seok Choi, Daejeon, KR;

Suk-Jo Kang, Daejeon, KR;

Janghyun Lee, Daejeon, KR;

Ji Youn Min, Daejeon, KR;

Dongmin Chun, Daejeon, KR;

Si-Eun Sung, Daejeon, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/117 (2010.01); A61K 31/713 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
C12N 15/117 (2013.01); A61K 31/713 (2013.01); C12N 15/113 (2013.01); C12N 15/1131 (2013.01); C12N 2310/17 (2013.01); C12N 2310/31 (2013.01); C12N 2310/315 (2013.01); C12N 2310/531 (2013.01); Y02A 50/385 (2018.01); Y02A 50/393 (2018.01);
Abstract

The present disclosure provides a pharmaceutical composition for treating cancer comprising an RNA oligonucleotide having a particular sequence and structure. Specifically, when a cell line is treated with an RNA oligonucleotide having specific sequence and helical bend structure according to the present disclosure, the expression of ISG56 is increased and apoptosis of cancer cells is induced. Thus, a composition comprising the RNA oligonucleotide can be used as an anticancer agent.


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