The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

Jun. 22, 2015
Applicant:

Seoul National University R&db Foundation, Seoul, KR;

Inventors:

Byung Gee Kim, Seoul, KR;

Yun Hee Choi, Seoul, KR;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/10 (2006.01); C12N 1/14 (2006.01); C12N 1/20 (2006.01); C12P 19/00 (2006.01); C12P 19/18 (2006.01); C12Q 1/48 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1051 (2013.01); C12N 1/14 (2013.01); C12N 1/20 (2013.01); C12P 19/00 (2013.01); C12P 19/18 (2013.01); C12Q 1/48 (2013.01); C12Y 204/01065 (2013.01); G01N 2333/91102 (2013.01);
Abstract

The present invention provides an α-1,3 fucosyltransferase mutant having an increased expression level of soluble protein and increased activity, a DNA encoding the α-1,3 fucosyltransferase mutant, a recombinant vector comprising the DNA encoding the α-1,3 fucosyltransferase mutant, a host cell transformed with the recombinant DNA vector, an extract of the host cell, a method for producing 3-fucosyloligosaccharide, a method for preparing an α-1,3 fucosyltransferase mutant, and a method for screening an α-1,3 fucosyltransferase mutant. The α-1,3 fucosyltransferase mutant of the present invention has a significantly increased soluble protein expression level and activity.


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