The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2019
Filed:
Apr. 05, 2017
Hanall Biopharma Co., Ltd., Daejeon, KR;
Sung Wuk Kim, Gyeonggi-do, KR;
Seung Kook Park, Seoul, KR;
Jae Kap Jeong, Daejeon, KR;
Hyea Kyung Ahn, Gyeonggi-do, KR;
Min Sun Kim, Gyeonggi-do, KR;
Eun Sun Kim, Seoul, KR;
Hae-Young Yong, Gyeonggi-do, KR;
Dongok Shin, Gyeonggi-do, KR;
Yeon Jung Song, Gyeonggi-do, KR;
Tae Hyoung Yoo, Gyeonggi-do, KR;
HANALL BIOPHARMA CO., LTD., Daejeon, KR;
Abstract
The present disclosure relates to an isolated anti-FcRn antibody, which is an antibody binding to FcRn (stands for neonatal Fc receptor, also called FcRP, FcRB or Brambell receptor) that is a receptor with a high affinity for IgG or a fragment thereof, a method of preparing thereof, a composition for treating autoimmune disease, which comprises the antibody, and a method of treating and diagnosing autoimmune diseases using the antibody. The FcRn-specific antibody according to the present disclosure binds to FcRn non-competitively with IgG to reduce serum pathogenic auto-antibody levels, and thus can be used for the treatment of autoimmune diseases.