The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

Dec. 28, 2016
Applicant:

Beijing Innocare Pharma Tech Co., Ltd., Beijing, CN;

Inventors:

Xiangyang Chen, Beijing, CN;

Yucheng Pang, Beijing, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/06 (2006.01); A61K 31/437 (2006.01); C07D 471/22 (2006.01); A61K 31/519 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61P 37/00 (2006.01); A61P 35/00 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/22 (2013.01); A61K 31/437 (2013.01); A61K 31/519 (2013.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01);
Abstract

The present invention relates to pyrazole fused-ring derivatives, their preparation methods, and use thereof in medicine. In particular, the present invention relates to a novel derivative represented by formula (I), and a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising the same and a method for preparing the same. The present invention also relates to use of the derivatives and the pharmaceutically acceptable salt thereof or the pharmaceutical composition comprising the same in the preparation of therapeutic agents, in particular Bruton tyrosine kinase inhibitors, and preparing a medicament for treating and/or preventing tumors and inflammatory associated diseases. The substituents on formula (I) are defined same as in the specification.


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