The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2019
Filed:
Aug. 02, 2016
Applicant:
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
Inventors:
Nupam P. Mahajan, Tampa, FL (US);
Kiran N. Mahajan, Tampa, FL (US);
Nicholas J. Lawrence, Tampa, FL (US);
Harshani R. Lawrence, Tampa, FL (US);
Assignee:
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/506 (2006.01); C07D 405/12 (2006.01); C07D 403/12 (2006.01); C07D 405/14 (2006.01); C07D 401/12 (2006.01); C07D 239/48 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 405/12 (2013.01); A61P 35/00 (2018.01); C07D 239/48 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01);
Abstract
Described are cancer therapies and anti-cancer compounds. In particular, disclosed are inhibitors of ACK1 tyrosine kinase and their use in the treatment of cancer. Methods of screening for new ACK1 tyrosine kinase inhibitors are also disclosed. In specific example, compound having Formula I are disclosed.