The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 02, 2019
Filed:
Dec. 14, 2015
Applicants:
Eudendron S.r.l., Varese, IT;
Universita' Degli Studi Di Milano, Milan, IT;
Inventors:
Mauro Angiolini, Varese, IT;
Fabio Zuccotto, Varese, IT;
Anna Bernardi, Milan, IT;
Francesco Airaghi, Milan, IT;
Assignees:
EUDENDRON S.R.L., Varese, IT;
UNIVERSITA' DEGLI STUDI DI MILANO, Milan, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/56 (2006.01); C07D 405/14 (2006.01); C07D 403/14 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); A61P 25/28 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07D 261/20 (2006.01);
U.S. Cl.
CPC ...
C07D 231/56 (2013.01); A61P 25/28 (2018.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); C07D 261/20 (2013.01); C07D 403/12 (2013.01); C07D 403/14 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01);
Abstract
The present invention relates to novel heterocyclic derivatives having general formula (I) and their therapeutic use for diseases such as cancer, inflammation, pain, autoimmune diseases or neurodegenerative diseases like Alzheimer's or Parkinson's disease that can be treated by modulation of certain protein kinases. Compounds of formula (I) can be used for treatment of patients who do not respond to kinase inhibition therapy that comprises currently available medications.