The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

May. 12, 2016
Applicant:

Council of Scientific and Industrial Research, New Delhi, IN;

Inventors:

Dumbala Srinivasa Reddy, Pune, IN;

Vasudevan Natarajan, Maharashtra, IN;

Gorakhnath Rajaram Jachak, Maharashtra, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/56 (2006.01); A61K 31/47 (2006.01); C07B 33/00 (2006.01); C07C 227/06 (2006.01);
U.S. Cl.
CPC ...
C07D 215/56 (2013.01); A61K 31/47 (2013.01); C07B 33/00 (2013.01); C07C 227/06 (2013.01);
Abstract

The present patent discloses a novel one pot two-step process for the synthesis of ivacaftor and related compounds of [Formula (I)], wherein R, R, R, R, R, R, Rand Arare as described above; its tautomers or pharmaceutically acceptable salts thereof starting from indole acetic acid amides.


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