The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

Dec. 23, 2015
Applicant:

Bergenbio Asa, Bergen, NO;

Inventors:

Jason John Shiers, Nottingham, GB;

John Paul Watts, Nottingham, GB;

Stuart Thomas Onions, Nottingham, GB;

Mohammed Abdul Quddus, Nottingham, GB;

Joseph William Wrigglesworth, Nottingham, GB;

Colin Peter Sambrook-Smith, Nottingham, GB;

Alan Naylor, Herts, GB;

Derek Londesbrough, Sunderland, GB;

Assignee:

BerGenBio ASA, Bergen, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 227/12 (2006.01); C07D 213/75 (2006.01); C07D 403/12 (2006.01); C07D 401/12 (2006.01); C07D 237/20 (2006.01); C07D 405/10 (2006.01); C07D 405/12 (2006.01); C07D 409/04 (2006.01); C07D 409/14 (2006.01); C07D 413/12 (2006.01); A61K 31/44 (2006.01); A61K 31/4427 (2006.01); A61K 31/4433 (2006.01); A61K 31/4436 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/4545 (2006.01); A61K 31/50 (2006.01); A61K 31/501 (2006.01); A61K 31/53 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07C 227/00 (2006.01);
U.S. Cl.
CPC ...
C07D 213/75 (2013.01); A61K 31/44 (2013.01); A61K 31/444 (2013.01); A61K 31/4427 (2013.01); A61K 31/4433 (2013.01); A61K 31/4436 (2013.01); A61K 31/4439 (2013.01); A61K 31/4545 (2013.01); A61K 31/50 (2013.01); A61K 31/501 (2013.01); A61K 31/53 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); C07C 227/00 (2013.01); C07C 227/12 (2013.01); C07D 237/20 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/10 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01);
Abstract

The invention is directed to compounds of general formula (I), and pharmaceutical compositions containing such compounds. The compounds and compositions have valuable pharmaceutical properties. In particular, they may be used for the treatment of cancer. Novel intermediates and novel methods of preparation are also disclosed.


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