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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10336697 B1

PDFFull Text
Expired
Date of Patent:
Jul. 02, 2019

Filed:

Jun. 15, 2016

Spiro[cyclobutane-1,3'-indolin]-2′-one derivatives as bromodomain inhibitors

Applicant:

Orion Corporation, Espoo, FI;

Inventors:

Ravi Kotrabasaiah Ujjinamatada, Anekal Taluk Bangalore, IN;

Susanta Samajdar, Bangalore, IN;

Chandrasekhar Abbineni, Hyderabad, IN;

Subhendu Mukherjee, Hooghly W. Bengal, IN;

Tero Linnanen, Turku, FI;

Gerd Wohlfahrt, Helsinki, FI;

Assignee:

ORION CORPORATION, , FI;

Attorney:

Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.

Primary Examiner:

Bruck Kifle

Int. Cl.
CPC ...
C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/04 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 417/06 (2006.01); C07D 451/06 (2006.01); C07D 453/02 (2006.01); C07D 209/96 (2006.01); A61P 37/02 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 209/96 (2013.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); A61P 37/02 (2018.01); C07D 401/04 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 403/04 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/06 (2013.01); C07D 451/06 (2013.01); C07D 453/02 (2013.01);
Abstract

The present invention provides novel spiro[cyclobutane-1,3'-indolin]-2′-one derivatives of formula (I) in which Cy, R, R, R, L, and m have the meaning given in the specification, and pharmaceutically acceptable salts thereof. The compounds of formula (I) are useful as bromodomain inhibitors in the treatment or prevention of diseases or disorders where bromodomain inhibition is desired.

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Ujjinamatada, Ravi. (2019). Spiro[cyclobutane-1,3'-indolin]-2′-one derivatives as bromodomain inhibitors (U.S. Patent No. 10336697). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10336697

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