The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 02, 2019

Filed:

Jul. 05, 2016
Applicant:

Public University Corporation Yokohama City University, Yokohama-Shi Kanagawa, JP;

Inventors:

Takuya Takahashi, Yokohama, JP;

Tomoyuki Miyazaki, Yokohama, JP;

Tetsuya Suhara, Chiba, JP;

Makoto Higuchi, Chiba, JP;

Meiei Cho, Chiba, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61M 36/14 (2006.01); A61K 51/04 (2006.01); C07C 319/20 (2006.01); C07C 323/49 (2006.01); C07F 7/22 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
A61K 51/04 (2013.01); A61K 51/00 (2013.01); C07B 59/001 (2013.01); C07B 59/004 (2013.01); C07C 319/20 (2013.01); C07C 323/49 (2013.01); C07F 7/22 (2013.01); C07B 2200/05 (2013.01);
Abstract

The present invention provides a compound represented by formula (I), a pharmaceutically acceptable salt thereof or a solvate thereof. (In the formula, each of A and Z independently represents CO, SO or SO; each of X and Y independently represents S or O; each of R-Rindependently represents a hydrogen atom, an alkyl group, an alkenyl group, an alkynyl group or a halogen group; each Rindependently represents an alkyl group, an alkenyl group, an alkynyl group or a halogen group; and n represents an integer of 0-4.) This compound is capable of specifically binding to an AMPA receptor, and shows extremely high brain uptake.


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